The eting room was silent, a true frontier, a perfect blend of theory and technology.
"Currently, this scaffold is still in the Animal Experint stage," Ivan said frankly, "but we have already used a simplified version in Clinical — ’Directional Collagen Induction Patch.’ It uses an electric field or magnetic field to induce collagen fibers to align directionally in the early stages of healing, creating the correct path for subsequent Cell migration. Sisi’s last Surgery used this technology, combined with fractional laser, achieving a nearly perfect smoothness."
He clicked the next page, revealing a striking title: "Scar Treatnt on the Market: What Works, What Doesn’t."
"Before discussing frontier technology, we must honestly face the current situation: scar treatnt is a massive market, leading to various treatnt thods, creams, patches, essential oils, etc. Whether these things are effective, I’m sorry to tell you, most lack sufficient evidence. But that’s not the answer they want. So today, I will provide you with an evidence-based guide that you can relay to Patients."
The slide displayed a classification table:
Category One: Supported by Clear Evidence
"Silicone formulations," Ivan said, "are the Gold Standard in scar treatnt, with the most ample evidence. This includes silicone patches, silicone gel. The chanism of action is multifaceted: it provides occlusion and moisturization, slight pressure, regulates the hydration state of keratinocytes, thereby reducing collagen synthesis. For Surgical scars, burn scars, hypertrophic scars, using it as soon as possible after wound healing and continuing for 3-6 months can significantly improve the height, hardness, and itching of scars."
"What’s the key? Early, continuous, and correct application. Many people give up after a few days, thinking it doesn’t work, or only apply it when they rember. Silicone needs to be used for 12-24 hours daily, sustained for several months. It’s not magic; it’s the cumulative effect of physical and biochemical processes."
He presented a research data chart: "Systematic reviews show that silicone treatnt can reduce scar thickness by an average of 30-50%, with an itchiness score reduction of 40%. It’s not a cure, but a significant improvent. For hypertrophic scars, it is the preferred non-Surgical treatnt; for keloids, it is part of a comprehensive treatnt."
"Pressure therapy, for post-burn hypertrophic scars, is an irreplaceable thod. Through continuous pressure of 20-30mmHg, it reduces local blood flow, inhibits fibroblast activity. It requires customized pressure garnts, worn for 23 hours a day, lasting for 6-12 months or even longer. Patient compliance is the biggest challenge, but the effect is definite."
"Corticosteroid injections, for hypertrophic scars and keloids, triamcinolone local injection is the standard treatnt. Once a month, 3-4 tis as a course of treatnt, can make the scar flatten, soften, and relieve itching. However, the side effects are significant: skin atrophy, capillary dilation, pignt changes, even risk of systemic absorption. It requires precise injection and dose control."
Category Two: Certain Evidence, but Limited Effect
"Onion extract formulations," Ivan clicked to the next page, showing a common brand gel on the market, "the representative product is derma. In vitro experints show onion extract has anti-inflammatory and fibroblast proliferation inhibition effects, but Clinical research results are inconsistent. So studies show slight improvent for new scars, but mostly ineffective for mature scars. My evaluation is: you can try, but don’t expect too much, and definitely not as the main treatnt."
He continued: "Vitamin E, this is the most widely circulated ’scar removal magic’ among the public. But the fact is, high-quality Clinical studies have not been able to confirm its efficacy. Conversely, so studies show Vitamin E could cause contact dermatitis, even worsen scars. My advice is: not recomnded, especially not for wounds that have not completely healed."
"Aloe vera," he said, "has soothing effects for sunburns and mild skin irritation, but for pathological scars, there is no reliable evidence. It can be used as a moisturizer, but don’t expect scar removal effects."
Category Three: Insufficient or Ineffective Evidence
Ivan’s tone beca serious: "Lavender essential oil, tea tree essential oil, rosehip oil, and various ’natural’ essential oils," he said, "these are promoted as ’miraculous scar removal’ products on social dia, lacking rigorous Clinical research support. They may have certain moisturizing effects, but cannot change the histological structure of scars. More serious, essential oils may cause allergic reactions; for new scars, this irritation might be counterproductive."
"Oral collagen supplents, this is a huge market, but logically it doesn’t hold water. Consud collagen is broken down into amino acids in the digestive tract and cannot be directed to skin scars. Even if it reaches them, it cannot integrate into existing scar tissue. This is a tax on wisdom, don’t waste money, I’m sorry, please forgive , I an no offense to anyone, just stating objective facts."
"Various ’scar removal patches’, ’scar removal essence’, ’scarless cream’," he displayed several product photos, beautifully packaged, with exaggerated promotion, "these products mostly contain unknown ingredients, with so even secretly adding hormones. They exploit Patients’ anxiety, charging high fees, but the effect cannot be verified. My warning is: be wary of any product that promises ’complete scarlessness’, ’quick scar removal’, dicine has no such miracle."
The eting room remained silent, these straightforward words touched many hearts in attendance, who have seen too many Patients deceived by false advertising.
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